1200-2000

REGISTRATION

Chair: 

Steve Oliver (Cambridge, UK) and  Richard Reece (Manchester, UK)

1600-1615    

Welcome      

1615-1715    

Opening Keynote Lecture
Mike Snyder (Yale, USA): Analysis of transcription and regulatory networks in yeast using Omics techniques

1715-1800   

Celebratory Lecture
Jean Beggs (Edinburgh, UK): Yeast transformation 30 years on.

1830-2000    

WELCOME RECEPTION

Manchester Town Hall, Albert Square, Manchester, M60 2LA

Jane Mellor (Oxford, UK) and  Ed Louis (Nottingham, UK)

0830-0915    

Susan Gasser (Basel, Switzerland): Maintenance of genome integrity

0915-1000    

Martin Kupiec (Tel Aviv, Israel): Telomere length control in yeast: vertical and horizontal views

1000-1030    

Hot-topic Speaker: Olivier Gadal (Toulouse, France): High-resolution statistical mapping reveals gene territories in live yeast

1030-1100   

BREAK, COFFEE

Workshop 1A: Chromosome Transactions

Theatre A: Chair: Bik Tye (Ithaca, USA)

Workshop 2: Control of Gene Expression

Theatre B: Chair: Brenda Andrews (Toronto, Canada), Andy Sharrocks (Manchester, UK)

Christos Andreadis (Heraklion, Greece): Genome-wide analyses point to a new role of Saccharomyces cerevisiae Rad9 protein under physiological conditions.

Susana Rodriguez-Navarro (Valencia, Spain): A tale of coupling, Sus1 function in transcription and mRNA export.

Rodrigo Bermejo (Milano, Italy): Topological mechanisms protecting the integrity of replicating chromosomes.

Bernard Turcotte (Montréal, Canada): Transcriptional regulation of non-fermentable carbon utilization.

Tim Hughes (Toronto, Canada): Global similarity and characteristic differences in intrinsic nucleosome preference of regulatory sequences between yeast and human.

Kuangyu Yen (Penn State, USA): Transcriptional regulatory proteins target specific nucleosomes in the Saccharomyces genome.

Gavin Sherlock (Texas A&M, USA): Molecular characterization of the adaptive landscape in asexually evolving populations of Saccharomyces cerevisiae.

Anna Drinnenberg (MIT, USA): RNAi in budding yeast

Workshop 1B: From the genetic map to ecology and evolution (in memory of Bob Mortimer)

Theatre A: Chair: Duccio Cavalieri (Firenze, Italy)

Dr Ivan Liachko (Ithaca, USA): Evolutionary study of replication origins by comparative functional genomics.

Rachel Patton McCord (Harvard, USA): High-resolution DNA binding specificity analysis of yeast transcription factors.

Michaela Freeland (Cambridge, UK): Conservation of high flux-control (HFC) genes of yeast following the whole-genome duplication (WGD).

Nuno Mira (Lisboa, Portugal): Adaptation and resistance to acetic acid in Saccharomyces cerevisiae mediated by the Haa1p-regulon.

Enikö Zörgö (Ås, Norway): Quantitative analysis of heterosis in yeast.

Florian Schulze (Göttingen, Sweden): Degradation of yeast transcription factor Gcn4 requires a C-terminal nuclear localization signal in the cyclin Pcl5.

Sylvie Dequin (Montpellier, France): The genome sequence of Saccharomyces cerevisiae EC1118 reveals multiple gene transfer events that have shaped the genome of wine yeasts.

Mordechai Choder (Haifa, Israel): 'Coordinators', a novel class of shuttling factors that modulate all stages of gene expression in yeast.

1300-1600    

LUNCH, POSTER SESSIONS, BIOINFORMATICS ARENA, SPEAKER'S CORNER, COFFEE

1400-1600    

Bioinformatics Arena (Theatre A) –  Presentations and demonstrations from SGD and other bioinformatic resources

1400-1600    

POSTER SESSION (even number poster delegates available by their poster)

1400-1445    

Speaker's Corner:  (Rm 2.27) Susan Gasser (Basel, Switzerland), Ed Louis (Nottingham, UK), Kevin Verstrepen (Leuven, Belgium), Chris Brown (Harvard, USA)

1500-1545    

Speaker’s Corner: Martin Kupiec (Tel Aviv, Israel), Jure Piskur, (Lund, Sweden)

Daniela Delneri (Manchester, UK) and Steve Oliver (Cambridge, UK)

1600-1645    

Ed Louis (Nottingham, UK): Population genomics and evolution in Saccharomyces yeasts

1645-1730    

Maitreya Dunham (Seattle, USA): Genomic analysis of experimental evolution in yeasts

1730-1800    

Hot-topic Speaker: Jure Piskur (Lund, Sweden): Formation of novel chromosomes in yeast

18.00-1830

Hot-topic Speaker: Kevin Verstrepen (Leuven, Belgium): Subtelomeres accelerate the pace of gene family evolution

1830-2000    

POSTER SESSION (odd number poster delegates available by their posters). Free beer, courtesy of SABMiller

Anne Donaldson (Aberdeen, UK) and Iain Hagan (Manchester, UK)

0830-0915    

Virginia Zakian (Princeton, USA): Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae

0915-1000    

Kathy Gould (Vanderbilt, USA): Structural and functional analysis of the anaphase-promoting complex

1000-1030    

Hot-topic Speaker: Michael Polymenis (Texas A&M, USA): Linkage of metabolism to the cell division machinery 

1030-1100    

BREAK, COFFEE

Workshop 3A: Cell cycle and morphogenesis

Theatre A: Chair: Anne Donaldson (Aberdeen, UK)

Workshop 4: Signal transduction

Theatre B: Chair: Stefan Hohmann (Göteborg, Sweden) and Mike Stark (Dundee, UK)

Alberto Sanchez-Diaz (Manchester, UK): Recruitment of the Inn1 protein to the cleavage site during cytokinesis in budding yeast 

Evelyne Dubois (Bruxelles, Belgium): Tor pathway phosphatase PP2A is required for rapamycin-induced promoter binding of GATA-factors, Gln3 and Gat1.

Isabelle Sagot (Bordeaux, France): Individual fate of yeast facing quiescence reveals that nutrient sensing overrides cell cycle signals.

Lars-Göran Ottosson (Göteborg, Sweden): Robustness and fragility in the yeast High Osmolarity Glycerol (HOG) signal transduction pathway.

Jennifer Hood-DeGrenier (Wellesley, USA): Mitotic cyclins in the cytoplasmic compartment are important for cell wall integrity in Saccharomyces cerevisiae.

Marta Rubio-Texeira (Leuven, Belgium): Specific dipeptide analogs induce constitutive, Gap1-dependent activation of PKA and interfere with vacuolar sorting of the transceptor.

Michael Stark (Dundee, UK): Efficient chromosome bi-orientation and the tension checkpoint in Saccharomyces cerevisiae, both require Bir1p.

Laura Palmer (Penn State, USA): RRD1, a component of the TOR signalling pathway, affects anaesthetic response in Saccharomyces cerevisiae.

Workshop 3B: Systems & Synthetic Biology

Theatre A: Chair: Hans Westerhoff (Manchester, UK)

Helen Causton (Columbia, USA): Phenotypic diversity and the genetics of gene expression.

Clara Bermejo (Carnegie Inst., USA): Hxt5 keeps 'the door ajar'.

Rick Dunn (Manchester, UK): Investigation of growth rate and metabolite production for Saccharomyces cerevisiae grown under turbidostat conditions.

Susan Nicholls (Aberdeen, UK): The conservation of a heat shock response in an obligate pathogen of warm-blooded animals.

Greg Amoutzias (Gent, Belgium): Post-translational regulation has a major impact on gene retention following whole-genome duplication.

Andy Truman (Boston, USA): MAP kinase signaling specificity.

Uros Petrovic (Ljubljana, Slovenia): Identification of biologically relevant chemical-genetic subprofiles.

Ruben Ghillebert (Heverlee, Belgium): Degradation of Pi-transporters in S. cerevisiae by Pho4-dependent and Pho4-independent mechanisms

1300-1600    

LUNCH, POSTER SESSIONS, SPEAKER'S CORNER, COFFEE

1400-1600    

POSTER SESSION (even number poster delegates available by their posters)

1400-1445    

Speaker’s Corner: (Rm 2.27) André Goffeau (Louvain-la-Neuve, Belgium), Francesc Posas (Barcelona, Spain), Blanche Schwappach (Manchester, UK), Dennis Thiele (Durham, USA)

Stefan Hohmann (Göteborg, Sweden) and Mike Stark (Dundee, UK)

1600-1645    

Mike Hall (Basel, Switzerland): Regulation of cell growth via TOR and PKA

1645-1730    

Francesc Posas (Barcelona, Spain): Control of stress responses by the yeast Hog1 stress-activated kinase.

1730-1800    

Hot-topic Speaker: Francosie Roelants (Berkley, USA): A novel protein kinase network that regulates the function of phospholipid flippases

1800-1900

1800-2000

Speaker’s Corner: (Rm 2.27): Isabel Sa Correia (Lisboa, Portugal), Diethard Mattanovich (Wien, Austria)

POSTER SESSION (odd number poster delegates available by their posters). Cash bar

Katherine Smart (Nottingham, UK) and David Archer (Nottingham, UK)

0845-0915    

Hot-topic Speaker: Diethard Mattanovich (Wien, Austria): Engineering Pichia pastoris in the genomics era.

0915-1000    

Merja Penttila (Helsinki, Finland): Yeasts as production hosts for bulk chemicals

1000-1030    

Hot-topic Speaker: Isabel Sa Correia (Lisbon, Portugal):  Genome-wide requirements for maximum tolerance to ethanol and acids in Saccharomyces cerevisiae 

1030-1100

BREAK, COFFEE

Chair: Joanna Rytka (Warszawa, Poland), Terry Cooper (Memphis, USA)

1100-1145      

Blanche Schwappach (Manchester, UK): Getting stuck in the right membrane - recent progress in understanding the biogenesis of tail-anchored proteins

1145-1230      

Kathryn Ayscough (Sheffield, UK): The role of actin in endocytosis

1230-1300      

Hot-topic Speaker: Miroslava Opekarova (Praha, Czech Republic): Stable structural and functional compartmentation of the plasma membrane

1300-1400    

LUNCH

1300-1430    

Meeting of the Finance & Policy Committee (Room 2.2)

1500 Onwards

1930   

TOURS/ FREE AFTERNOON

Meeting and dinner for YEAST Editorial Board (Venue to be announced)

Richard Reece (Manchester, UK) and Andy Sharrocks (Manchester, UK)

0830-0915    

Frank Holstege (Utrecht, Netherlands): Understanding regulatory circuitry through expression-profile phenotypes 

0915-1000    

Shelley Berger (Philadelphia, USA): Histone acetylation regulates cellular lifespan in S. cerevisiae

1000-1030    

Hot-topic Speaker: Brenda Andrews (Toronto, Canada): A two-colour cell array screen reveals interdependent roles for histone chaperones and a chromatin boundary regulator in cell cycle-dependent gene repression

1030-1100

BREAK, COFFEE

Workshop 5A: Yeasts as Cell Factories

Theatre A: Chair: Katherine Smart (Nottingham, UK)

Workshop 6: Yeasts & Disease

Theatre B: Chair: Mick Tuite (Canterbury, UK), Ian Macreadie (Melbourne, Australia)

Yoshifumi Jigami (Tsukuba, Japan): Yeasts as host cells to produce humanized glycoproteins and selenomethionyl proteins.

Carol Munro (Aberdeen, UK): Regulation of chitin synthesis and cell wall remodelling in Candida albicans.

Hideki Tohda (Yokohama, Japan): Schizosaccharomyces pombe minimum genome factory.

Joris Winderickx (Heverlee, Belgium): Building yeast models to study tau-related neurodegenerative diseases.

Paul Klaassen (Delft, Netherlands): Isolation of industrial pentose fermenting yeast strains.

Sabrina Büttner (Graz, Austria): Alpha-synuclein kills aged yeast depending on mitochondrial function.

Michael Naesby (Allschwil, Switzerland): Yeast Artificial Chromosomes for random assembly of biosynthetic pathways in S. cerevisiae.

Alexander Goldberg (Montreal, Canada): The spatiotemporal dynamics of a modular metabolic network that regulates longevity in yeast. The chronological aging of yeast is an ontogenetic program.

Workshop 5B: Protein trafficking

Theatre A: Chair: Joanna Rytka (Warszawa, Poland)

Manfred Schmitt (Saarbrücken, Germany): Mechanistic insights into ER/cytosol retrotranslocation of the A/B toxins ricin and K28 in yeast.

Bik Tye (Ithaca, USA): A defective MCM helicase predisposes yeast to aneuploidy and accelerated proliferation.

Bruno André (Bruxelles, Belgium): The ubiquitin code of yeast permease trafficking.

Yury Chernoff (Atlanta, USA): Role of the short amino acid stretches in species specificity of prion conversion.

Alexander Goldberg (Montreal, Canada): An intraperoxisomal signaling cascade initiates peroxisome division by triggering the stepwise remodeling of lipid composition of the peroxisomal membrane.

Nadejda Koloteva-Levin (Canterbury, UK): How do yeast prions form spontaneously?

Teresa Zoladek (Warszawa, Poland): Localization of Rsp5 ubiquitin ligase to multiple sites in yeast cells depends on C2, WW domains and nuclear localization and export signals in the Hect domain.

Vitaly Kushnirov (Moscow, Russia): Fragmentation of prion polymers in yeast: its determinants and the role in species barrier.

LUNCH, SPEAKER'S CORNER, POSTER SESSION

Lubomira Stateva (Manchester, UK) and Al Brown (Aberdeen, UK)

1400-1445    

Judith Berman (Minnesota, USA): Genome stability and instability in the pathogenic yeast Candida albicans.

1445-1530    

Ken Haynes (London, UK): Glycosylation and hypervirulence in Candida glabrata

1530-1600    

Hot-topic Speaker: Candida Lucas (Braga, Portugal): The O-acyltransferase Gup1 is essential for Candida albicans morphogenesis and other virulence factors.

Dave Lydall (Newcastle, UK) and Peter Piper (Sheffield, UK)

1630-1715    

Ian Macreadie (Melbourne, Australia): Exploiting yeast to find chemo preventatives for Alzheimer's disease

1715-1800    

Dennis Thiele (Durham, USA): Understanding human diseases of metal homeostasis with yeast

1900             

CONFERENCE DINNER AT MANCHESTER UNITED FOOTBALL CLUB, OLD TRAFFORD

Douglas Kell (Manchester, UK) and Mick Tuite (Canterbury, UK)

0900-0945    

Yitzhak Pilpel (Rehovot, Israel): Coping with genetic and non-genetic stress in yeast

0945-1030    

Mike Tyers (Edinburgh, UK): Global analysis of the budding yeast kinome

1030-1100    

Hot-topic Speaker: Fritz Roth (Harvard, USA): Using parallel sequencing to map genetic interactions.

1100-1130      

BREAK, COFFEE

Steve Oliver (Cambridge, UK) and Richard Reece (Manchester, UK)

1140-1225    

Closing Keynote Lecture

Susan Lindquist (Whitehead Institute, USA): Prions and chaperones: protein folding driving evolutionary change 

1225-1235

André Goffeau (Louvain-la-Neuve, Belgium): In Memorium: ­Piotr Slonimski

1235-1300    

Ian Dawes (Sydney, Australia): The International Community of Yeast Geneticists & Molecular Biologists

1300-1320    

Joanna Rytka (Warszawa, Poland): Invitation to Yeast 2011

1320-1330    

Closing Remarks